America, 1899!
The end of the Wild West era has begun as lawmen hunt down the last outlaw gangs. Those who do not want to surrender or succumb are killed.
After a robbery goes wrong in the western town of Blackwater, Arthur Morgan and the Van der Linde gang are forced to go on the run. Along with federal agents and the nation's best bounty hunters, the gang must rob, rob, and fight their way across America's wild heartland to survive.
As deepening internal divisions threaten to tear the gang apart, Arthur must choose between his own ideals and loyalty to the gang that raised him.