Jimmy Neutron embarks on another adventure filled with brand-new inventions and gadgets.
Aliens from Twonkus-3 - the annual comet that passes over Retroville - have invaded the city, threatening everything in their path.
When the aliens hear music, they get restless and get even bigger.
As Jimmy, it's up to you to find combinations of everyday objects and turn them into inventions that will defeat the Twonkus-3 aliens.
Secret gadgets hidden in each level give you enhanced bonuses.